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Let's say that my opponent has 1 single untapped character with 2 defense. It is my turn and I have 2 or 3 characters, so I will attack multiple times. During my first attack my opponent flipped 1 or 2 blue icons. The question is: During my second attack, my opponent's character will start the battling with 2 defense or with 4 defense? Also, the same may happen with the orange icon if I got a way to attack twice with the same player in a turn?

The Battle Icons you flip are only effective for that individual battle. Attack and Defense increases will not carry over.
Source: Wizards of the Coast (2019-02-11)    【Link to Ruling】
Tags: Battle Icons