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Since you have to discard your hand to activate Dino-Chomp!, can you still play Dino-Chomp! if it is the only card in your hand?

Yes. Discarding your hand is not a cost, but an effect of the card. If your hand is empty, youll discard nothing.
Source: Wizards of the Coast (2019-02-28)    【Link to Ruling】
Tags: Dino-Chomp!